I’ve given tips on how to disable USB ports via security software or changing Windows USB register files, but the simplest way to secure a USB port is to block it.
The folks at Earth-Trek developed a swanky USB lock which uses the UFD shaped key to also house the USB locks.
As you can see in the picture, the key uses a mechanical lever type setup to insert the USB lock, then detach the key from the seated lock and the USB port is blocked.
Judging by the picture it might not be hard to tear out the USB lock, but you’ll probably make enough noise in the attempt to draw attention.
Source: Earth-Trek
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